Unraveling the mysteries of aging.
Research conducted by David Sinclair and colleagues shows that, in mice, treatment with the NAD precursor NMN mitigates age-related DNA damage and averts DNA damage from radiation exposure.
DNA repair is essential for cell vitality, cell survival, and cancer prevention, yet cells’ ability to patch up damaged DNA declines with age for reasons not fully understood.
Now, research led by scientists at Harvard Medical School (HMS) reveals a critical step in a molecular chain of events that allows cells to mend their broken DNA.
Their Experiments in mice suggest way to prevent DNA damage from aging and radiation.